Exploring Diabetes Wellbeing: A Panel Data Analysis of Physical Activity, Depressive Symptoms, and Health-Related Quality of Life in Korea
DOI:
https://doi.org/10.54259/sehatrakyat.v5i2.7449Keywords:
Physical Activity, Depressive Symptom, Health-Related Quality of Life, DiabetesAbstract
Background: Negative health outcome is the result of both physical activity and depressive symptoms aggravating each other. The potential impact of the interaction between physical activity and depressive symptoms on health-related quality of life is not well understood. This study was conducted to investigate the association between physical activity, depressive symptoms, and health-related quality of life in diabetic patients in Korea. Methods: Data was collected from 1,472 participants with diabetes mellitus from the Korea Health Panel Survey (KHPS) in 2020 after missing values were excluded. Sociodemographic characteristics, physical activity, depressive symptoms, and EQ -5D scores were obtained from the KHPS. To determine the association between physical activity, depressive symptoms, and health-related quality of life, linear regression analysis was performed after controlling for confounding variables. Results: Results showed that physical activity and depressive symptoms had a significant impact on health-related quality of life. After adjustment for gender, age, occupation, and alcohol consumption, physical activity and depressive symptoms remained strongly associated. The incidence of depressive symptoms was 0.74 higher with irregular physical activity than among those who took part in regular physical activity (p < 0.05). Conclusion: Physical activity and depression symptoms are correlated with health-related quality of life. Physical activity intensity and depressive symptoms should be considered when developing programs to improve health-related quality of life.
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AlSawahli, H., Mpyet, C. D., Ezzelarab, G., Hassanin, I., Shalaby, M., Safa, O., & Almansour, A. (2021). Population-based cross-sectional prevalence survey of diabetes and diabetic retinopathy in Sohag—Egypt, 2019. BMJ Open, 11(6), e047757. https://doi.org/10.1136/bmjopen-2020-047757
Alshayban, D., & Joseph, R. (2020). Health-related quality of life among patients with type 2 diabetes mellitus in Eastern Province, Saudi Arabia: A cross-sectional study. PLOS ONE, 15(1), e0227573. https://doi.org/10.1371/journal.pone.0227573
Bae, J. H., Han, K.-D., Ko, S.-H., Yang, Y. S., Choi, J. H., Choi, K. M., Kwon, H.-S., & Won, K. C. (2022). Diabetes Fact Sheet in Korea 2021. Diabetes & Metabolism Journal, 46(3), 417–426. https://doi.org/10.4093/dmj.2022.0106
Cannata, F., Vadalà, G., Russo, F., Papalia, R., Napoli, N., & Pozzilli, P. (2020). Beneficial Effects of Physical Activity in Diabetic Patients. Journal of Functional Morphology and Kinesiology, 5(3), 70. https://doi.org/10.3390/jfmk5030070
CDC. (2020). National Diabetes Statistics Report 2020 Estimates of Diabetes and Its Burden in the United States.
Cheng, H.-P., Chen, C.-H., Lin, M.-H., Wang, C.-S., Yang, Y.-C., Lu, F.-H., Wu, J.-S., & Lin, S.-I. (2019). Gender differences in the relationship between walking activity and sleep disturbance among community-dwelling older adult with diabetes in Taiwan. Journal of Women and Aging, 31(2), 108–116. https://doi.org/10.1080/08952841.2017.1413830
Domínguez-Domínguez, A., Martínez-Guardado, I., Domínguez-Muñoz, F. J., Barrios-Fernandez, S., Morenas-Martín, J., Garcia-Gordillo, M. A., & Carlos-Vivas, J. (2021). Association between the Level of Physical Activity and Health-Related Quality of Life in Type 1 Diabetes Mellitus. A Preliminary Study. Journal of Clinical Medicine, 10(24), 5829. https://doi.org/10.3390/jcm10245829
Eker, S. (2018). Prevalence of Depression Symptoms in Diabetes Mellitus. Open Access Macedonian Journal of Medical Sciences, 6(2), 340–343. https://doi.org/10.3889/oamjms.2018.085
Etxeberria, I., Urdaneta, E., & Galdona, N. (2019). Factors associated with health-related quality of life (HRQoL): Differential patterns depending on age. Quality of Life Research, 28(8), 2221–2231. https://doi.org/10.1007/s11136-019-02182-0
Ghandour, R., Mikki, N., Abu Rmeileh, N. M. E., Jerdén, L., Norberg, M., Eriksson, J. W., & Husseini, A. (2018). Complications of type 2 diabetes mellitus in Ramallah and al-Bireh: The Palestinian Diabetes Complications and Control Study (PDCCS). Primary Care Diabetes, 12(6), 547–557. https://doi.org/10.1016/j.pcd.2018.07.002
Jeong, M. (2021). Factors Associated with Depressive Symptoms in Korean Adults with Diabetes Mellitus: A Cross-Sectional Study. Healthcare, 9(8), 1049. https://doi.org/10.3390/healthcare9081049
Kim, C., Jin, H., & Dusing, G. J. (2023). Employment conditions and leisure-time physical activity among Korean workers: A longitudinal study (2009–2019). BMC Public Health, 23(1), 955. https://doi.org/10.1186/s12889-023-15766-w
Kim, C., Teo, C., Nielsen, A., & Chum, A. (2023). Macro-level gender equality and women’s depressive symptoms in South Korea: A longitudinal study. Social Psychiatry and Psychiatric Epidemiology, 58(3), 383–393. https://doi.org/10.1007/s00127-022-02335-6
Kim, D.-J. (2018). Effects of Physical Activity on Depression in Adults with Diabetes. Osong Public Health and Research Perspectives, 9(4), 143–149. https://doi.org/10.24171/j.phrp.2018.9.4.02
Kim, G. E., Jo, M.-W., & Shin, Y.-W. (2020). Increased prevalence of depression in South Korea from 2002 to 2013. Scientific Reports, 10(1), 16979. https://doi.org/10.1038/s41598-020-74119-4
Kim, M.-C. (2011). Metabolic syndrome, lifestyle risk factors, and distal colon adenoma: A retrospective cohort study. World Journal of Gastroenterology, 17(35), 4031. https://doi.org/10.3748/wjg.v17.i35.4031
Kim, S., & Kim, D. (2025). Mental health help-seeking among Korean men: The influence of stigma, masculine norms, and face. BMC Psychology, 13(1), 461. https://doi.org/10.1186/s40359-025-02793-y
Kim, U., & Park, Y.-S. (2000). Confucianism and family values: Their impact on educational achievement in Korea. Zeitschrift Für Erziehungswissenschaft, 3(2), 229–249. https://doi.org/10.1007/s11618-000-0023-6
Krzemińska, S., Bąk, E., Polanská, A., Hašová, K., Laurinc, M., Zrubcová, D., & Młynarska, A. (2023). Does gender affect health-related quality of life in patients with type 2 diabetes (ADDQoL) in Central European countries? Annals of Agricultural and Environmental Medicine, 30(2), 296–305. https://doi.org/10.26444/aaem/161584
Marquez, D. X., Aguiñaga, S., Vásquez, P. M., Conroy, D. E., Erickson, K. I., Hillman, C., Stillman, C. M., Ballard, R. M., Sheppard, B. B., Petruzzello, S. J., King, A. C., & Powell, K. E. (2020). A systematic review of physical activity and quality of life and well-being. Translational Behavioral Medicine, 10(5), 1098–1109. https://doi.org/10.1093/tbm/ibz198
Martins, K. A. K. F., Mascarenhas, L. P. G., Morandini, M., Cat, M. N. L., Pereira, R. M., Carvalho, J. R. de, Lacerda Filho, L. de, & França, S. N. (2018). Health-related quality of life in a cohort of youths with type 1 diabetes. Revista Da Associação Médica Brasileira, 64(11), 1038–1044. https://doi.org/10.1590/1806-9282.64.11.1038
McIntyre, E., Lauche, R., Frawley, J., Sibbritt, D., Reddy, P., & Adams, J. (2019). Physical activity and depression symptoms in women with chronic illness and the mediating role of health-related quality of life. Journal of Affective Disorders, 252, 294–299. https://doi.org/10.1016/j.jad.2019.04.057
Noh, J.-W., Kim, J., Park, J., Kim, H., & Kwon, Y. D. (2015). Gender Difference in Relationship between Health-Related Quality of Life and Work Status. PLOS ONE, 10(12), e0143579. https://doi.org/10.1371/journal.pone.0143579
Oh, S. W., Shin, S.-A., Yun, Y. H., Yoo, T., & Huh, B.-Y. (2004). Cut-off Point of BMI and Obesity-Related Comorbidities and Mortality in Middle-Aged Koreans. Obesity Research, 12(12), 2031–2040. https://doi.org/10.1038/oby.2004.254
Ong, K. L., Stafford, L. K., McLaughlin, S. A., Boyko, E. J., Vollset, S. E., Smith, A. E., Dalton, B. E., Duprey, J., Cruz, J. A., Hagins, H., Lindstedt, P. A., Aali, A., Abate, Y. H., Abate, M. D., Abbasian, M., Abbasi-Kangevari, Z., Abbasi-Kangevari, M., Abd ElHafeez, S., Abd-Rabu, R., … Vos, T. (2023). Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: A systematic analysis for the Global Burden of Disease Study 2021. The Lancet, 402(10397), 203–234. https://doi.org/10.1016/S0140-6736(23)01301-6
Park, S. E., Ko, S.-H., Kim, J. Y., Kim, K., Moon, J. H., Kim, N. H., Han, K. D., Choi, S. H., & Cha, B. S. (2025). Diabetes Fact Sheets in Korea 2024. Diabetes & Metabolism Journal, 49(1), 24–33. https://doi.org/10.4093/dmj.2024.0818
Park, S.-G., Min, K.-B., Chang, S.-J., Kim, H.-C., & Min, J.-Y. (2009). Job stress and depressive symptoms among Korean employees: The effects of culture on work. International Archives of Occupational and Environmental Health, 82(3), 397–405. https://doi.org/10.1007/s00420-008-0347-8
Pilozzi, A., Carro, C., & Huang, X. (2020). Roles of β-Endorphin in Stress, Behavior, Neuroinflammation, and Brain Energy Metabolism. International Journal of Molecular Sciences, 22(1), 338. https://doi.org/10.3390/ijms22010338
Puciato, D., Bączkowicz, D., & Rozpara, M. (2023). Correlations between physical activity and quality of life in entrepreneurs from Wrocław, Poland. BMC Sports Science, Medicine and Rehabilitation, 15(1), 13. https://doi.org/10.1186/s13102-023-00624-4
Ranjan, R., Nath, S., & Sarkar, S. (2020). Association between depression, anxiety and quality of life among patients with diabetes mellitus and/or hypertension in a tertiary care railway hospital in India: A cross-sectional study. Indian Journal of Psychiatry, 62(5), 555. https://doi.org/10.4103/psychiatry.IndianJPsychiatry_794_19
Renn, B. N., Obetz, V., & Feliciano, L. (2020). Comorbidity of depressive symptoms among primary care patients with diabetes in a federally qualified health center. Journal of Health Psychology, 25(9), 1303–1309. https://doi.org/10.1177/1359105318755260
Roh, S., Mun, W., & Kim, G. (2024). Associations between Physical Activity, Mental Health, and Suicidal Behavior in Korean Adolescents: Based on Data from 18th Korea Youth Risk Behavior Web-Based Survey (2022). Behavioral Sciences, 14(3), 160. https://doi.org/10.3390/bs14030160
Shamshirgaran, S. M., Stephens, C., Alpass, F., & Aminisani, N. (2020). Longitudinal assessment of the health-related quality of life among older people with diabetes: Results of a nationwide study in New Zealand. BMC Endocrine Disorders, 20(1). https://doi.org/10.1186/s12902-020-0519-4
Shi, K., Zhu, Y., Lv, J., Sun, D., Pei, P., Du, H., Chen, Y., Yang, L., Han, B., Stevens, R., Chen, J., Chen, Z., Li, L., & Yu, C. (2023). Association of physical activity with risk of chronic kidney disease in China: A population-based cohort study. Journal of Sport and Health Science. https://doi.org/https://doi.org/10.1016/j.jshs.2023.07.004
Shi, L., Shu, X.-O., Li, H., Cai, H., Liu, Q., Zheng, W., Xiang, Y.-B., & Villegas, R. (2013). Physical activity, smoking, and alcohol consumption in association with incidence of type 2 diabetes among middle-aged and elderly Chinese men. PloS One, 8(11), e77919. https://doi.org/10.1371/journal.pone.0077919
Williams, D. M., Jones, H., & Stephens, J. W. (2022). Personalized Type 2 Diabetes Management: An Update on Recent Advances and Recommendations. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Volume 15, 281–295. https://doi.org/10.2147/DMSO.S331654
World Health Organization. (2000). International guide for monitoring alcohol consumption and related harm. World Health Organization.
Zare, F., Ameri, H., Madadizadeh, F., & Aghaei, M. R. (2020). Health-related quality of life and its associated factors in patients with type 2 diabetes mellitus. SAGE Open Medicine, 8, 2050312120965314. https://doi.org/10.1177/2050312120965314
Zuo, X., Dong, Z., Zhang, P. P., Zhang, P. P., Chang, G., Xiang, Q., Zhu, X., Zhou, J., Qiao, C., Yang, Y., Qin, Y. Y., & Lou, P. (2020). Effects of cognitive behavioral therapy on sleep disturbances and quality of life among adults with type 2 diabetes mellitus: A randomized controlled trial. Nutrition, Metabolism and Cardiovascular Diseases, 30(11), 1980–1988. https://doi.org/10.1016/j.numecd.2020.06.024
Zurita-Cruz, J. N., Manuel-Apolinar, L., Arellano-Flores, M. L., Gutierrez-Gonzalez, A., Najera-Ahumada, A. G., & Cisneros-González, N. (2018). Health and quality of life outcomes impairment of quality of life in type 2 diabetes mellitus: A cross-sectional study. Health and Quality of Life Outcomes, 16(1), 94. https://doi.org/10.1186/s12955-018-0906-y
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